BDBM50584383 CHEMBL5080162::EN300-5601139
SMILES Cc1cn(cn1)-c1cc(N)cc(c1)C(F)(F)F
InChI Key InChIKey=WWTGXYAJVXKEKL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50584383
TargetNuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 2.00E+4nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
Affinity DataIC50: 2.17E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 2.00E+4nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair